Erwinaze: treatment for patients with acute lymphoblastic leukemia (ALL)

If you, your child or someone else you care for has recently been diagnosed with acute lymphoblastic leukemia (ALL), you will probably want to find out more about the disease itself and treatment for ALL.

Here you can find out what causes ALL, how ALL is treated and why, and about Erwinaze – recently approved by the United States Food and Drug Administration (FDA) for use alongside chemotherapy in ALL.


Erwinaze Use

ERWINAZE is a drug used to treat cancer of the white blood cells called Acute Lymphoblastic Leukemia (ALL) in patients who have had an allergic reaction to similar products. It is designed to be given with other medications used to treat cancer.


Selected Risk Information about Erwinaze™ (asparaginase Erwinia chrysanthemi)

CONTRAINDICATIONS: Do not use with history of serious side effects, e.g., allergy to Erwinaze OR inflammation of the pancreas, blood clots or bleeding following therapy with any asparaginase.

WARNINGS AND PRECAUTIONS: Do not continue to use if serious allergic reactions OR inflammation of the pancreas occur. Blood sugar levels should be checked to see if treatment is needed. Do not continue to use if blood clots or abnormal bleeding occur. Pregnant women should use only if clearly needed. Do not use if breast-feeding.

COMMON SIDE EFFECTS: Serious allergic reactions (tightness in throat, abnormal swelling/redness or difficulty breathing), some of which may be life-threatening; inflammation of the pancreatitis (stomach pain); abnormal blood clotting (may have headache, pain in leg, arm, or chest); unusual bleeding; liver problems; nausea, vomiting, and abnormal blood sugar levels (may be thirsty or frequently urinate). Notify your doctor of any troublesome side effects.

Click here for Full Prescribing Information to discuss with your doctor.

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The reimbursement hotline is available for patients, physicians or healthcare provider staff to assist with reimbursement or coverage questions. The Community Access Patient Program is our version of a Patient Assistance Program (PAP) and may provide patients with free drug, if they qualify, as well as assist with benefits investigation and alternative coverage assistance.